Professor Willie Hamilton is professor of primary care diagnostics at the University of Exeter. His research has had a major impact on improving earlier diagnosis of cancer in the UK. He was clinical lead on the NICE guideline `Referral for suspected cancer’ in 2015, which has contributed to a reduction in the number of avoidable cancer deaths in the UK. He and his team have produced risk assessment tools for all major adult cancers. Wilie is co-principal investigator on a CRUK award called CanTest, studying tests for cancer in primary care, and co-leads the Translational Research Exchange at Exeter, bringing together mathematical experts and clinicians.